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FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis

Neutrophils are the most abundant inflammatory cells at the earliest stages of wound healing and play important roles in wound repair and fibrosis. Formyl peptide receptor 1 (FPR-1) is abundantly expressed on neutrophils and has been shown to regulate their function, yet the importance of FPR-1 in f...

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Detalles Bibliográficos
Autores principales: Leslie, Jack, Millar, Ben J.M., del Carpio Pons, Alicia, Burgoyne, Rachel A., Frost, Joseph D., Barksby, Ben S., Luli, Saimir, Scott, Jon, Simpson, A. John, Gauldie, Jack, Murray, Lynne A., Finch, Donna K., Carruthers, Alan M., Ferguson, John, Sleeman, Matthew A., Rider, David, Howarth, Rachel, Fox, Christopher, Oakley, Fiona, Fisher, Andrew J., Mann, Derek A., Borthwick, Lee A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101152/
https://www.ncbi.nlm.nih.gov/pubmed/32102985
http://dx.doi.org/10.1172/jci.insight.125937