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FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis
Neutrophils are the most abundant inflammatory cells at the earliest stages of wound healing and play important roles in wound repair and fibrosis. Formyl peptide receptor 1 (FPR-1) is abundantly expressed on neutrophils and has been shown to regulate their function, yet the importance of FPR-1 in f...
Autores principales: | Leslie, Jack, Millar, Ben J.M., del Carpio Pons, Alicia, Burgoyne, Rachel A., Frost, Joseph D., Barksby, Ben S., Luli, Saimir, Scott, Jon, Simpson, A. John, Gauldie, Jack, Murray, Lynne A., Finch, Donna K., Carruthers, Alan M., Ferguson, John, Sleeman, Matthew A., Rider, David, Howarth, Rachel, Fox, Christopher, Oakley, Fiona, Fisher, Andrew J., Mann, Derek A., Borthwick, Lee A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101152/ https://www.ncbi.nlm.nih.gov/pubmed/32102985 http://dx.doi.org/10.1172/jci.insight.125937 |
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