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Targeted gene silencing in vivo by platelet membrane–coated metal-organic framework nanoparticles
Small interfering RNA (siRNA) is a powerful tool for gene silencing that has been used for a wide range of biomedical applications, but there are many challenges facing its therapeutic use in vivo. Here, we report on a platelet cell membrane–coated metal-organic framework (MOF) nanodelivery platform...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101224/ https://www.ncbi.nlm.nih.gov/pubmed/32258408 http://dx.doi.org/10.1126/sciadv.aaz6108 |