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Human iPSC-derived mature microglia retain their identity and functionally integrate in the chimeric mouse brain
Microglia, the brain-resident macrophages, exhibit highly dynamic functions in neurodevelopment and neurodegeneration. Human microglia possess unique features as compared to mouse microglia, but our understanding of human microglial functions is largely limited by an inability to obtain human microg...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101330/ https://www.ncbi.nlm.nih.gov/pubmed/32221280 http://dx.doi.org/10.1038/s41467-020-15411-9 |