Cargando…

Optimization of Docetaxel Loading Conditions in Liposomes: proposing potential products for metastatic breast carcinoma chemotherapy

Docetaxel (DTX) was loaded in nanoliposomes based on a new remote loading method using mannitol and acetic acid as hydration buffer. DTX loading conditions were optimized, and the final formulations were prepared according to the best parameters which were HSPC/mPEG2000-DSPE/Chol (F1), HSPC/mPEG2000...

Descripción completa

Detalles Bibliográficos
Autores principales: Vakili-Ghartavol, Roghayyeh, Rezayat, Seyed Mahdi, Faridi-Majidi, Reza, Sadri, Kayvan, Jaafari, Mahmoud Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101339/
https://www.ncbi.nlm.nih.gov/pubmed/32221371
http://dx.doi.org/10.1038/s41598-020-62501-1