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Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the α-d-phosphohexomutase superfamily

Human phosphoglucomutase 1 (PGM1) is an evolutionary conserved enzyme that belongs to the ubiquitous and ancient α-d-phosphohexomutases, a large enzyme superfamily with members in all three domains of life. PGM1 catalyzes the bi-directional interconversion between α-d-glucose 1-phosphate (G1P) and α...

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Detalles Bibliográficos
Autores principales: Backe, Paul Hoff, Laerdahl, Jon K., Kittelsen, Lene Svendsen, Dalhus, Bjørn, Mørkrid, Lars, Bjørås, Magnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101342/
https://www.ncbi.nlm.nih.gov/pubmed/32221390
http://dx.doi.org/10.1038/s41598-020-62548-0