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Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking

Circulating tumour DNA (ctDNA) allows tracking of the evolution of human cancers at high resolution, overcoming many limitations of tissue biopsies. However, exploiting ctDNA to determine how a patient’s cancer is evolving in order to aid clinical decisions remains difficult. This is because ctDNA i...

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Detalles Bibliográficos
Autores principales: Cresswell, George D., Nichol, Daniel, Spiteri, Inmaculada, Tari, Haider, Zapata, Luis, Heide, Timon, Maley, Carlo C., Magnani, Luca, Schiavon, Gaia, Ashworth, Alan, Barry, Peter, Sottoriva, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101390/
https://www.ncbi.nlm.nih.gov/pubmed/32221288
http://dx.doi.org/10.1038/s41467-020-15047-9