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Upregulation of Glutamate Transporter 1 by Clavulanic Acid Administration and Attenuation of Allodynia and Hyperalgesia in Neuropathic Rats

INTRODUCTION: Clavulanic acid (CLAV) is structurally similar to ceftriaxone, a potent stimulator of glial GlutamateTransporter-1 (GLT-1) expression. The present study aims at exploring the anti-nociceptive effects of CLAV, a beta-lactamase inhibitor in rats underwent sciatic nerve Chronic Constricti...

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Detalles Bibliográficos
Autores principales: Amin, Bahareh, Avaznia, Mahmoud, Noorani, Reihaneh, Mehri, Soghra, Hosseinzadeh, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Neuroscience Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101523/
https://www.ncbi.nlm.nih.gov/pubmed/32231771
http://dx.doi.org/10.32598/bcn.10.4.799.2