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A Green Tea-Derived Polyphenol, Epigallocatechin-3-Gallate, Inhibits IκB Kinase Activation and IL-8 Gene Expression in Respiratory Epithelium

Interleukin-8 (IL-8) is a principle neutrophil chemoattractant and activator in humans. There is interest in developing novel pharmacological inhibitors of IL-8 gene expression as a means for modulating inflammation in disease states such as acute lung injury. Herein we determined the effects of epi...

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Detalles Bibliográficos
Autores principales: Chen, Philip C., Wheeler, Derek S., Malhotra, Vivek, Odoms, Kelli, Denenberg, Alvin G., Wong, Hector R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kluwer Academic Publishers-Plenum Publishers 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101574/
https://www.ncbi.nlm.nih.gov/pubmed/12238566
http://dx.doi.org/10.1023/A:1019718718977