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A Green Tea-Derived Polyphenol, Epigallocatechin-3-Gallate, Inhibits IκB Kinase Activation and IL-8 Gene Expression in Respiratory Epithelium
Interleukin-8 (IL-8) is a principle neutrophil chemoattractant and activator in humans. There is interest in developing novel pharmacological inhibitors of IL-8 gene expression as a means for modulating inflammation in disease states such as acute lung injury. Herein we determined the effects of epi...
Autores principales: | Chen, Philip C., Wheeler, Derek S., Malhotra, Vivek, Odoms, Kelli, Denenberg, Alvin G., Wong, Hector R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kluwer Academic Publishers-Plenum Publishers
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101574/ https://www.ncbi.nlm.nih.gov/pubmed/12238566 http://dx.doi.org/10.1023/A:1019718718977 |
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