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High incidence of graft failure in children receiving CD34+ augmented elutriated allografts for nonmalignant diseases

T-cell depletion of the marrow graft using counterflow centrifugal elutriation reduces the risk of graft-versus-host disease (GVHD). However, because of high rates of graft failure and relapse, elutriation alone has not improved survival. We have carried out a phase II clinical trial in 54 pediatric...

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Detalles Bibliográficos
Autores principales: McDonough, C H, Jacobsohn, D A, Vogelsang, G B, Noga, S J, Chen, A R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101579/
https://www.ncbi.nlm.nih.gov/pubmed/12796786
http://dx.doi.org/10.1038/sj.bmt.1704071