Simvastatin attenuates the lipopolysaccharideinduced inflammatory response of rat pulmonary microvascular endothelial cells by downregulating toll-like receptor 4 expression

OBJECTIVE: The therapeutic potential of simvastatin as an anti-inflammatory agent was explored by investigating its effect on the lipopolysaccharide (LPS)-induced inflammatory response in rat pulmonary microvascular endothelial cells (RPMVECs). METHODS: RPMVECs were isolated and the mRNA and protein...

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Detalles Bibliográficos
Autores principales: Li, Yi, Ding, Jian-yong, Ge, Biao-xue, Miao, Chang-hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101868/
https://www.ncbi.nlm.nih.gov/pubmed/32288932
http://dx.doi.org/10.2478/s11536-013-0245-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101868/
https://www.ncbi.nlm.nih.gov/pubmed/32288932
http://dx.doi.org/10.2478/s11536-013-0245-7

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