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MicroRNA-34a Suppresses Autophagy in Alveolar Type II Epithelial Cells in Acute Lung Injury by Inhibiting FoxO3 Expression

Excessive autophagic activity of alveolar type II epithelial (AT-II) cells is one of the main causes of acute lung injury (ALI); however, the underlying molecular mechanism remains to be determined. The microRNAs (miRNAs) are involved with autophagy in many diseases. The objective of this study was...

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Detalles Bibliográficos
Autores principales: Song, Lan, Zhou, Fangliang, Cheng, Lijuan, Hu, Mei, He, Yingchun, Zhang, Bo, Liao, Duanfang, Xu, Zhaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101993/
https://www.ncbi.nlm.nih.gov/pubmed/28321785
http://dx.doi.org/10.1007/s10753-017-0537-1