Apelin-12 and its structural analog enhance antioxidant defense in experimental myocardial ischemia and reperfusion

This study investigated the effects of peptide apelin-12 (H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH, A12) and its novel structural analog (H-(N(α)Me)Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Nle-Pro-Phe-OH, AI) on myocardial antioxidant enzyme activities, lipid peroxidation, and reactive oxygen...

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Detalles Bibliográficos
Autores principales: Pisarenko, O. I., Lankin, V. Z., Konovalova, G. G., Serebryakova, L. I., Shulzhenko, V. S., Timoshin, A. A., Tskitishvili, O. V., Pelogeykina, Yu. A., Studneva, I. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102085/
https://www.ncbi.nlm.nih.gov/pubmed/24599747
http://dx.doi.org/10.1007/s11010-014-2008-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102085/
https://www.ncbi.nlm.nih.gov/pubmed/24599747
http://dx.doi.org/10.1007/s11010-014-2008-4

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