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Studying neuroprotective effect of Atorvastatin as a small molecule drug on high glucose-induced neurotoxicity in undifferentiated PC12 cells: role of NADPH oxidase

Overproduction of reactive oxygen species (ROS) by NADPH oxidase (NOX) activation has been considered the essential mechanism induced by hyperglycemia in various tissues. However, there is no comprehensive study on the role of NOXs in high glucose (HG)-induced toxic effect in neural tissues. Recentl...

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Detalles Bibliográficos
Autores principales: Rayegan, Samira, Dehpour, Ahmad Reza, Sharifi, Ali Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102122/
https://www.ncbi.nlm.nih.gov/pubmed/27476541
http://dx.doi.org/10.1007/s11011-016-9883-1