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Skeletal muscle targeting in vivo electroporation-mediated HGF gene therapy of bleomycin-induced pulmonary fibrosis in mice

Lung fibrosis is a common feature of interstitial lung diseases, and apoptosis and fibrinogenesis play critical roles in its formation and progression. Hepatocyte growth factor (HGF) is one of the ideal therapeutic agents for prevention of lung fibrosis because of its antiapoptotic and fibrinolytic...

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Detalles Bibliográficos
Autores principales: Umeda, Yukio, Marui, Tsutomu, Matsuno, Yukihiro, Shirahashi, Koyo, Iwata, Hisashi, Takagi, Hisato, Matsumoto, Kunio, Nakamura, Toshikazu, Kosugi, Atsushi, Mori, Yoshio, Takemura, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102183/
https://www.ncbi.nlm.nih.gov/pubmed/15197407
http://dx.doi.org/10.1038/labinvest.3700098