Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma

The cytotoxic granzyme B (GrB)/perforin pathway has been traditionally viewed as a primary mechanism that is used by cytotoxic lymphocytes to eliminate allogeneic, virally infected and/or transformed cells. Although originally proposed to have intracellular and extracellular functions, upon the disc...

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Detalles Bibliográficos
Autores principales: Boivin, Wendy Anne, Cooper, Dawn Michelle, Hiebert, Paul Ryan, Granville, David James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102238/
https://www.ncbi.nlm.nih.gov/pubmed/19770840
http://dx.doi.org/10.1038/labinvest.2009.91

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102238/
https://www.ncbi.nlm.nih.gov/pubmed/19770840
http://dx.doi.org/10.1038/labinvest.2009.91

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