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Inhibitory effects of glycopyrronium, formoterol, and budesonide on coronavirus HCoV-229E replication and cytokine production by primary cultures of human nasal and tracheal epithelial cells

BACKGROUND: Coronavirus 229E (HCoV-229E), one of the causes of the common cold, exacerbates chronic obstructive pulmonary disease (COPD) and bronchial asthma. Long-acting muscarinic antagonists and β(2)-agonists and inhaled corticosteroids inhibit the exacerbation of COPD and bronchial asthma caused...

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Detalles Bibliográficos
Autores principales: Yamaya, Mutsuo, Nishimura, Hidekazu, Deng, Xue, Sugawara, Mitsuru, Watanabe, Oshi, Nomura, Kazuhiro, Shimotai, Yoshitaka, Momma, Haruki, Ichinose, Masakazu, Kawase, Tetsuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Respiratory Society. Published by Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102607/
https://www.ncbi.nlm.nih.gov/pubmed/32094077
http://dx.doi.org/10.1016/j.resinv.2019.12.005