Cargando…

Implications of altered replication fidelity on the evolution and pathogenesis of coronaviruses

RNA virus evolution results from viral replication fidelity and mutational robustness in combination with selection. Recent studies have confirmed the impact of increased fidelity on RNA virus replication and pathogenesis; however, the impact of decreased fidelity is less defined. Coronaviruses have...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, Everett C, Denison, Mark R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102773/
https://www.ncbi.nlm.nih.gov/pubmed/22857992
http://dx.doi.org/10.1016/j.coviro.2012.07.005