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Implications of altered replication fidelity on the evolution and pathogenesis of coronaviruses
RNA virus evolution results from viral replication fidelity and mutational robustness in combination with selection. Recent studies have confirmed the impact of increased fidelity on RNA virus replication and pathogenesis; however, the impact of decreased fidelity is less defined. Coronaviruses have...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Published by Elsevier B.V.
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102773/ https://www.ncbi.nlm.nih.gov/pubmed/22857992 http://dx.doi.org/10.1016/j.coviro.2012.07.005 |