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Coordinated regulation of IFITM1, 2 and 3 genes by an IFN-responsive enhancer through long-range chromatin interactions

Interferon-induced transmembrane protein (IFITM) 1, 2 and 3 genes encode a family of interferon (IFN)-induced transmembrane proteins that block entry of a broad spectrum of pathogens. However, the transcriptional regulation of these genes, especially whether there exist any enhancers and their roles...

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Detalles Bibliográficos
Autores principales: Li, Ping, Shi, Ming-Lei, Shen, Wen-Long, Zhang, Zhang, Xie, De-Jian, Zhang, Xiang-Yuan, He, Chao, Zhang, Yan, Zhao, Zhi-Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102783/
https://www.ncbi.nlm.nih.gov/pubmed/28511927
http://dx.doi.org/10.1016/j.bbagrm.2017.05.003