Cargando…

Airway proteases: an emerging drug target for influenza and other respiratory virus infections

To enter into airway epithelial cells, influenza, parainfluenza- and coronaviruses rely on host cell proteases for activation of the viral protein involved in membrane fusion. One protease, transmembrane protease serine 2 (TMPRSS2) was recently proven to be crucial for hemagglutinin cleavage of some...

Descripción completa

Detalles Bibliográficos
Autores principales: Laporte, Manon, Naesens, Lieve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102789/
https://www.ncbi.nlm.nih.gov/pubmed/28414992
http://dx.doi.org/10.1016/j.coviro.2017.03.018