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The roles of cytosolic quality control proteins, SGTA and the BAG6 complex, in disease

SGTA is a co-chaperone that, in collaboration with the complex of BAG6/UBL4A/TRC35, facilitates the biogenesis and quality control of hydrophobic proteins, protecting them from the aqueous cytosolic environment. This work includes targeting tail-anchored proteins to their resident membranes, sorting...

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Detalles Bibliográficos
Autores principales: Benarroch, Rashi, Austin, Jennifer M., Ahmed, Fahmeda, Isaacson, Rivka L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102839/
https://www.ncbi.nlm.nih.gov/pubmed/30635083
http://dx.doi.org/10.1016/bs.apcsb.2018.11.002