Miconazole Contributes to NRF2 Activation by Noncanonical P62-KEAP1 Pathway in Bladder Cancer Cells

PURPOSE: Nuclear factor (erythroid-derived 2)-like 2, also known as NFE2L2 or NRF2, a transcription factor capable of upregulating antioxidant response element (ARE)-mediated expression and cytoprotective proteins, plays critical roles in chemoprevention, inflammation and aging. NRF2 has recently be...

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Detalles Bibliográficos
Autores principales: Tsai, Te-Fu, Chen, Po-Chun, Lin, Yi-Chia, Chou, Kuang-Yu, Chen, Hung-En, Ho, Chao-Yen, Lin, Ji-Fan, Hwang, Thomas I-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102888/
https://www.ncbi.nlm.nih.gov/pubmed/32273683
http://dx.doi.org/10.2147/DDDT.S227892