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HIF-1α, TWIST-1 and ITGB-1, associated with Tumor Stiffness, as Novel Predictive Markers for the Pathological Response to Neoadjuvant Chemotherapy in Breast Cancer

PURPOSE: To investigate the relationship between hypoxia-inducible factor 1-alpha (HIF-1α), Twist family BHLH transcription factor 1 (TWIST-1), and β1 integrin (ITGB-1) expression and tumor stiffness, and evaluate performance of HIF-1α, TWIST-1, and ITGB-1 alone and in combination with Ki-67 for pre...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Zhang, Shuo, Gao, Song, Ma, Yan, Tan, Xueying, Kang, Ye, Ren, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102918/
https://www.ncbi.nlm.nih.gov/pubmed/32273760
http://dx.doi.org/10.2147/CMAR.S246349