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Shp2-mediated MAPK pathway regulates ΔNp63 in epithelium to warrant corneal innervation and homeostasis

Corneal nerve fibers serving sensory, reflex and neurotrophic functions sustains the corneal homeostasis and transparency to warrant the normal visual function. It remains unknown whether corneal epithelium is also reciprocally important for the corneal innervation. Herein, we generated a compound t...

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Detalles Bibliográficos
Autores principales: Okada, Yuka, Zhang, Yujin, Zhang, Lingling, Yeh, Lung-Kun, Wang, Yen-Chiao, Saika, Shizuya, Liu, Chia-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102931/
https://www.ncbi.nlm.nih.gov/pubmed/31653968
http://dx.doi.org/10.1038/s41374-019-0338-2