GO: a functional reporter system to identify and enrich base editing activity

Base editing (BE) is a powerful tool for engineering single nucleotide variants (SNVs) and has been used to create targeted mutations in cell lines, organoids and animal models. Recent development of new BE enzymes has provided an extensive toolkit for genome modification; however, identifying and i...

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Detalles Bibliográficos
Autores principales: Katti, Alyna, Foronda, Miguel, Zimmerman, Jill, Diaz, Bianca, Zafra, Maria Paz, Goswami, Sukanya, Dow, Lukas E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102966/
https://www.ncbi.nlm.nih.gov/pubmed/32112097
http://dx.doi.org/10.1093/nar/gkaa124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102966/
https://www.ncbi.nlm.nih.gov/pubmed/32112097
http://dx.doi.org/10.1093/nar/gkaa124

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