The complex formed between a synthetic RNA aptamer and the transcription repressor TetR is a structural and functional twin of the operator DNA–TetR regulator complex

RNAs play major roles in the regulation of gene expression. Hence, designer RNA molecules are increasingly explored as regulatory switches in synthetic biology. Among these, the TetR-binding RNA aptamer was selected by its ability to compete with operator DNA for binding to the bacterial repressor T...

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Detalles Bibliográficos
Autores principales: Grau, Florian C, Jaeger, Jeannine, Groher, Florian, Suess, Beatrix, Muller, Yves A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102968/
https://www.ncbi.nlm.nih.gov/pubmed/32052019
http://dx.doi.org/10.1093/nar/gkaa083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102968/
https://www.ncbi.nlm.nih.gov/pubmed/32052019
http://dx.doi.org/10.1093/nar/gkaa083

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