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SENEBLOC, a long non-coding RNA suppresses senescence via p53-dependent and independent mechanisms

Long non-coding RNAs (lncRNAs) have emerged as important biological tuners. Here, we reveal the role of an uncharacterized lncRNA we call SENEBLOC that is expressed by both normal and transformed cells under homeostatic conditions. SENEBLOC was shown to block the induction of cellular senescence thr...

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Detalles Bibliográficos
Autores principales: Xu, Cheng Lin, Sang, Ben, Liu, Guang Zhi, Li, Jin Ming, Zhang, Xu Dong, Liu, Lian Xin, Thorne, Rick F, Wu, Mian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102969/
https://www.ncbi.nlm.nih.gov/pubmed/32030426
http://dx.doi.org/10.1093/nar/gkaa063