The cardenolide ouabain suppresses coronaviral replication via augmenting a Na(+)/K(+)-ATPase-dependent PI3K_PDK1 axis signaling

Cardenolides are plant-derived toxic substances. Their cytotoxicity and the underlying mechanistic signaling axes have been extensively documented, but only a few anti-viral activities of cardenolides and the associated signaling pathways have been reported. Previously, we reported that a variety of...

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Detalles Bibliográficos
Autores principales: Yang, Cheng-Wei, Chang, Hsin-Yu, Lee, Yue-Zhi, Hsu, Hsing-Yu, Lee, Shiow-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103114/
https://www.ncbi.nlm.nih.gov/pubmed/30053394
http://dx.doi.org/10.1016/j.taap.2018.07.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103114/
https://www.ncbi.nlm.nih.gov/pubmed/30053394
http://dx.doi.org/10.1016/j.taap.2018.07.028

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