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The cardenolide ouabain suppresses coronaviral replication via augmenting a Na(+)/K(+)-ATPase-dependent PI3K_PDK1 axis signaling

Cardenolides are plant-derived toxic substances. Their cytotoxicity and the underlying mechanistic signaling axes have been extensively documented, but only a few anti-viral activities of cardenolides and the associated signaling pathways have been reported. Previously, we reported that a variety of...

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Detalles Bibliográficos
Autores principales:	Yang, Cheng-Wei, Chang, Hsin-Yu, Lee, Yue-Zhi, Hsu, Hsing-Yu, Lee, Shiow-Ju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103114/ https://www.ncbi.nlm.nih.gov/pubmed/30053394 http://dx.doi.org/10.1016/j.taap.2018.07.028

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