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Molecular characterisation of RIG-I-like helicases in the black flying fox, Pteropus alecto

The RIG-I like helicases, RIG-I, mda5 and LGP2 are an evolutionarily conserved family of cytosolic pattern recognition receptors important in the recognition of viral RNA, and responsible for the innate induction of interferons and proinflammatory cytokines upon viral infection. Bats are natural res...

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Detalles Bibliográficos
Autores principales: Cowled, Christopher, Baker, Michelle L., Zhou, Peng, Tachedjian, Mary, Wang, Lin-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103216/
https://www.ncbi.nlm.nih.gov/pubmed/22166340
http://dx.doi.org/10.1016/j.dci.2011.11.008