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Non-viral siRNA delivery to the lung()

SiRNAs exert their biological effect by guiding the degradation of their cognate mRNA sequence, thereby shutting down the corresponding protein production (gene silencing by RNA interference or RNAi). Due to this property, siRNAs are emerging as promising therapeutic agents for the treatment of inhe...

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Detalles Bibliográficos
Autores principales: Thomas, Mini, Lu, James J., Chen, Jianzhu, Klibanov, Alexander M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103292/
https://www.ncbi.nlm.nih.gov/pubmed/17459519
http://dx.doi.org/10.1016/j.addr.2007.03.003