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Interactions of LSECtin and DC-SIGN/DC-SIGNR with viral ligands: Differential pH dependence, internalization and virion binding

The calcium-dependent lectins DC-SIGN and DC-SIGNR (collectively termed DC-SIGN/R) bind to high-mannose carbohydrates on a variety of viruses. In contrast, the related lectin LSECtin does not recognize mannose-rich glycans and interacts with a more restricted spectrum of viruses. Here, we analyzed w...

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Detalles Bibliográficos
Autores principales: Gramberg, Thomas, Soilleux, Elizabeth, Fisch, Tanja, Lalor, Patricia F., Hofmann, Heike, Wheeldon, Sophie, Cotterill, Andrew, Wegele, Anja, Winkler, Thomas, Adams, David H., Pöhlmann, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103327/
https://www.ncbi.nlm.nih.gov/pubmed/18083206
http://dx.doi.org/10.1016/j.virol.2007.11.001