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Transcriptional profiling of Vero E6 cells over-expressing SARS-CoV S2 subunit: Insights on viral regulation of apoptosis and proliferation

We have previously demonstrated that over-expression of spike protein (S) of severe acute respiratory syndrome coronavirus (SARS-CoV) or its C-terminal subunit (S2) is sufficient to induce apoptosis in vitro. To further investigate the possible roles of S2 in SARS-CoV-induced apoptosis and pathogene...

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Detalles Bibliográficos
Autores principales: Yeung, Yin-Shan, Yip, Chi-Wai, Hon, Chung-Chau, Chow, Ken Y.C., Ma, Iris C.M., Zeng, Fanya, Leung, Frederick C.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103328/
https://www.ncbi.nlm.nih.gov/pubmed/17961624
http://dx.doi.org/10.1016/j.virol.2007.09.016