Nucleocapsid protein of SARS-CoV activates interleukin-6 expression through cellular transcription factor NF-κB

High levels of interleukin-6 (IL-6) in the acute stage associated with lung lesions were found in SARS patients. To evaluate the mechanisms behind this event, we investigated the roles of SARS-CoV proteins in the regulation of IL-6. Results showed that the viral nucleocapsid (N) protein activated IL...

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Detalles Bibliográficos
Autores principales: Zhang, Xue, Wu, Kailang, Wang, Di, Yue, Xin, Song, Degui, Zhu, Ying, Wu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103332/
https://www.ncbi.nlm.nih.gov/pubmed/17490702
http://dx.doi.org/10.1016/j.virol.2007.04.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103332/
https://www.ncbi.nlm.nih.gov/pubmed/17490702
http://dx.doi.org/10.1016/j.virol.2007.04.009

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