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NS3 protein of hepatitis C virus regulates cyclooxygenase-2 expression through multiple signaling pathways

Hepatitis C virus (HCV) causes chronic hepatitis, which often results in the development of liver cirrhosis and hepatocellular carcinoma (HCC) worldwide. In this study, we demonstrated that the non-structural protein NS3 of HCV enhances cyclooxygenase-2 (COX-2) gene promoter activity, COX-2 mRNA exp...

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Detalles Bibliográficos
Autores principales: Lu, Lili, Wei, Liang, Peng, Guiqing, Mu, Yongxin, Wu, Kailang, Kang, Lei, Yan, Xiaohong, Zhu, Ying, Wu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103338/
https://www.ncbi.nlm.nih.gov/pubmed/17964630
http://dx.doi.org/10.1016/j.virol.2007.09.025