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Absence of E protein arrests transmissible gastroenteritis coronavirus maturation in the secretory pathway

A recombinant transmissible gastroenteritis coronavirus (rTGEV) in which E gene was deleted (rTGEV-ΔE) has been engineered. This deletion mutant only grows in cells expressing E protein (E(+) cells) indicating that E was an essential gene for TGEV replication. Electron microscopy studies of rTGEV-ΔE...

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Detalles Bibliográficos
Autores principales: Ortego, Javier, Ceriani, Juan E., Patiño, Cristina, Plana, Juan, Enjuanes, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103363/
https://www.ncbi.nlm.nih.gov/pubmed/17692883
http://dx.doi.org/10.1016/j.virol.2007.05.032