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Absence of E protein arrests transmissible gastroenteritis coronavirus maturation in the secretory pathway
A recombinant transmissible gastroenteritis coronavirus (rTGEV) in which E gene was deleted (rTGEV-ΔE) has been engineered. This deletion mutant only grows in cells expressing E protein (E(+) cells) indicating that E was an essential gene for TGEV replication. Electron microscopy studies of rTGEV-ΔE...
Autores principales: | Ortego, Javier, Ceriani, Juan E., Patiño, Cristina, Plana, Juan, Enjuanes, Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103363/ https://www.ncbi.nlm.nih.gov/pubmed/17692883 http://dx.doi.org/10.1016/j.virol.2007.05.032 |
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