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SARS vaccine based on a replication-defective recombinant vesicular stomatitis virus is more potent than one based on a replication-competent vector

A SARS vaccine based on a live-attenuated vesicular stomatitis virus (VSV) recombinant expressing the SARS-CoV S protein provides long-term protection of immunized mice from SARS-CoV infection (Kapadia, S.U., Rose, J. K., Lamirande, E., Vogel, L., Subbarao, K., Roberts, A., 2005. Long-term protectio...

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Detalles Bibliográficos
Autores principales: Kapadia, Sagar U., Simon, Ian D., Rose, John K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103385/
https://www.ncbi.nlm.nih.gov/pubmed/18396306
http://dx.doi.org/10.1016/j.virol.2008.03.002