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Formation of stable homodimer via the C-terminal α-helical domain of coronavirus nonstructural protein 9 is critical for its function in viral replication

Coronaviruses devote more than three quarters of their coding capacity to encode two large polyproteins (1a and 1ab polyproteins), which are proteolytically processed into 15–16 mature, nonstructural replicase proteins (nsp1 to 16). These cleavage products are believed to play essential roles in rep...

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Detalles Bibliográficos
Autores principales: Chen, Bo, Fang, Shouguo, Tam, James P., Liu, Ding Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103386/
https://www.ncbi.nlm.nih.gov/pubmed/19022466
http://dx.doi.org/10.1016/j.virol.2008.10.032