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Expansion and preservation of the functional activity of adult hematopoietic stem cells cultured ex vivo with a histone deacetylase inhibitor

Attempts to expand ex vivo the numbers of human hematopoietic stem cells (HSCs) without compromising their marrow repopulating capacity and their ability to establish multilineage hematopoiesis has been the subject of intense investigation. Although most such efforts have focused on cord blood HSCs,...

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Detalles Bibliográficos
Autores principales: Zimran, Eran, Papa, Luena, Djedaini, Mansour, Patel, Ami, Iancu‐Rubin, Camelia, Hoffman, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103619/
https://www.ncbi.nlm.nih.gov/pubmed/31950644
http://dx.doi.org/10.1002/sctm.19-0199