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Exosomal 2′,3′‐CNP from mesenchymal stem cells promotes hippocampus CA1 neurogenesis/neuritogenesis and contributes to rescue of cognition/learning deficiencies of damaged brain

Mesenchymal stem cells (MSCs) have been used in clinical studies to treat neurological diseases and damage. However, implanted MSCs do not achieve their regenerative effects by differentiating into and replacing neural cells. Instead, MSC secretome components mediate the regenerative effects of MSCs...

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Detalles Bibliográficos
Autores principales: Chen, Shih‐Yin, Lin, Meng‐chieh, Tsai, Jia‐Shiuan, He, Pei‐Lin, Luo, Wen‐Ting, Chiu, Ing‐Ming, Herschman, Harvey R., Li, Hua‐Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103625/
https://www.ncbi.nlm.nih.gov/pubmed/31943851
http://dx.doi.org/10.1002/sctm.19-0174