Cargando…

Retinoic Acid Exerts Disease Stage-Dependent Effects on Pristane-Induced Lupus

We previously showed that all-trans-retinoic acid (tRA), an active metabolite of vitamin A, exacerbated pre-existing autoimmunity in lupus; however, its effects before the development of autoimmunity are unknown. Here, using a pristane-induced model, we show that tRA exerts differential effects when...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdelhamid, Leila, Cabana-Puig, Xavier, Swartwout, Brianna, Lee, Jiyoung, Li, Song, Sun, Sha, Li, Yaqi, Ross, A. Catharine, Cecere, Thomas E., LeRoith, Tanya, Werre, Stephen R., Wang, Haifeng, Reilly, Christopher M., Luo, Xin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103630/
https://www.ncbi.nlm.nih.gov/pubmed/32265909
http://dx.doi.org/10.3389/fimmu.2020.00408