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Retinoic Acid Exerts Disease Stage-Dependent Effects on Pristane-Induced Lupus

We previously showed that all-trans-retinoic acid (tRA), an active metabolite of vitamin A, exacerbated pre-existing autoimmunity in lupus; however, its effects before the development of autoimmunity are unknown. Here, using a pristane-induced model, we show that tRA exerts differential effects when...

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Detalles Bibliográficos
Autores principales:	Abdelhamid, Leila, Cabana-Puig, Xavier, Swartwout, Brianna, Lee, Jiyoung, Li, Song, Sun, Sha, Li, Yaqi, Ross, A. Catharine, Cecere, Thomas E., LeRoith, Tanya, Werre, Stephen R., Wang, Haifeng, Reilly, Christopher M., Luo, Xin M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103630/ https://www.ncbi.nlm.nih.gov/pubmed/32265909 http://dx.doi.org/10.3389/fimmu.2020.00408

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