Acute Pannexin 1 Blockade Mitigates Early Synaptic Plasticity Defects in a Mouse Model of Alzheimer’s Disease

Synaptic loss induced by soluble oligomeric forms of the amyloid β peptide (sAβos) is one of the earliest events in Alzheimer’s disease (AD) and is thought to be the major cause of the cognitive deficits. These abnormalities rely on defects in synaptic plasticity, a series of events manifested as ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Flores-Muñoz, Carolina, Gómez, Bárbara, Mery, Elena, Mujica, Paula, Gajardo, Ivana, Córdova, Claudio, Lopez-Espíndola, Daniela, Durán-Aniotz, Claudia, Hetz, Claudio, Muñoz, Pablo, Gonzalez-Jamett, Arlek M., Ardiles, Álvaro O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103637/
https://www.ncbi.nlm.nih.gov/pubmed/32265655
http://dx.doi.org/10.3389/fncel.2020.00046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103637/
https://www.ncbi.nlm.nih.gov/pubmed/32265655
http://dx.doi.org/10.3389/fncel.2020.00046

Ejemplares similares