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Optimization and qualification of a functional anti-drug antibody assay for HIV-1 bnAbs
The recent identification of human monoclonal antibodies with broad and potent neutralizing activity against HIV-1 (bnAbs) has resulted in substantial efforts to develop these molecules for clinical use in the prevention and treatment of HIV-1 infection. As with any protein therapeutic drug product,...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103754/ https://www.ncbi.nlm.nih.gov/pubmed/31917969 http://dx.doi.org/10.1016/j.jim.2020.112736 |