Cargando…

Optimization and qualification of a functional anti-drug antibody assay for HIV-1 bnAbs

The recent identification of human monoclonal antibodies with broad and potent neutralizing activity against HIV-1 (bnAbs) has resulted in substantial efforts to develop these molecules for clinical use in the prevention and treatment of HIV-1 infection. As with any protein therapeutic drug product,...

Descripción completa

Detalles Bibliográficos
Autores principales: Seaman, Michael S., Bilska, Miroslawa, Ghantous, Fadi, Eaton, Amanda, LaBranche, Celia C., Greene, Kelli, Gao, Hongmei, Weiner, Joshua A., Ackerman, Margaret E., Garber, David A., Rosenberg, Yvonne J., Sarzotti-Kelsoe, Marcella, Montefiori, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103754/
https://www.ncbi.nlm.nih.gov/pubmed/31917969
http://dx.doi.org/10.1016/j.jim.2020.112736