Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

In response to transcription-blocking DNA damage, cells orchestrate a multi-pronged reaction, involving transcription-coupled DNA repair, degradation of RNA polymerase II (RNAPII), and genome-wide transcription shutdown. Here, we provide insight into how these responses are connected by the finding...

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Detalles Bibliográficos
Autores principales: Tufegdžić Vidaković, Ana, Mitter, Richard, Kelly, Gavin P., Neumann, Michelle, Harreman, Michelle, Rodríguez-Martínez, Marta, Herlihy, Anna, Weems, Juston C., Boeing, Stefan, Encheva, Vesela, Gaul, Liam, Milligan, Laura, Tollervey, David, Conaway, Ronald C., Conaway, Joan W., Snijders, Ambrosius P., Stewart, Aengus, Svejstrup, Jesper Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103762/
https://www.ncbi.nlm.nih.gov/pubmed/32142654
http://dx.doi.org/10.1016/j.cell.2020.02.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103762/
https://www.ncbi.nlm.nih.gov/pubmed/32142654
http://dx.doi.org/10.1016/j.cell.2020.02.009

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