Oncolytic vaccinia virus delivering tethered IL-12 enhances antitumor effects with improved safety

Immune checkpoint blockade is arguably the most effective current cancer therapy approach; however, its efficacy is limited to patients with “hot” tumors, warranting an effective approach to transform “cold” tumors. Oncolytic viruses (especially properly armed ones) have positive effects on almost e...

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Detalles Bibliográficos
Autores principales: Ge, Yan, Wang, Haiyan, Ren, Jinghua, Liu, Weilin, Chen, Lingjuan, Chen, Hongqi, Ye, Junjie, Dai, Enyong, Ma, Congrong, Ju, Songguang, Guo, Zong Sheng, Liu, Zuqiang, Bartlett, David L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103801/
https://www.ncbi.nlm.nih.gov/pubmed/32209602
http://dx.doi.org/10.1136/jitc-2020-000710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103801/
https://www.ncbi.nlm.nih.gov/pubmed/32209602
http://dx.doi.org/10.1136/jitc-2020-000710

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