An MXD1-derived repressor peptide identifies noncoding mediators of MYC-driven cell proliferation

MYC controls the transcription of large numbers of long noncoding RNAs (lncRNAs). Since MYC is a ubiquitous oncoprotein, some of these lncRNAs probably play a significant role in cancer. We applied CRISPR interference (CRISPRi) to the identification of MYC-regulated lncRNAs that are required for MYC...

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Detalles Bibliográficos
Autores principales: Raffeiner, Philipp, Hart, Jonathan R., García-Caballero, Daniel, Bar-Peled, Liron, Weinberg, Marc S., Vogt, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104257/
https://www.ncbi.nlm.nih.gov/pubmed/32156728
http://dx.doi.org/10.1073/pnas.1921786117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104257/
https://www.ncbi.nlm.nih.gov/pubmed/32156728
http://dx.doi.org/10.1073/pnas.1921786117

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